About hereditary angioedema

What is hereditary angioedema (HAE)?
HAE is a rare inherited disease that can cause sudden, unpredictable, and often severe swelling in specific parts of the body, including the abdomen, face, and throat.

HAE symptoms can resemble other conditions that cause swelling and pain, such as severe allergic reactions or stomach problems. Misdiagnosis or delayed diagnosis of HAE is common, so it’s important to talk to your doctor about HAE as a possible cause of your symptoms.

Learn more about HAE, including what causes attacks, early symptoms to look for, and triggers for attacks
How do I treat HAE attacks once they’ve started?
Acute attacks in the abdomen, face, or throat may be treated by taking a C1-INH concentrate, such as BERINERT, which is used to treat attacks on demand. BERINERT is approved for patient self-administration after proper training by a healthcare professional.

Self-administration at the first sign of an attack with BERINERT can help put you in control of your HAE and increase your independence.

Discover fast, sustained relief from HAE attacks with BERINERT


BERINERT is a fast-acting, on-demand treatment for attacks of swelling caused by hereditary angioedema (HAE). BERINERT works at the root cause of HAE attacks by adding functioning C1-INH to your body, a key protein that is either missing or non-functioning in people with HAE. With the right training, you can self-administer BERINERT, so you can get relief when and where you need it.

Learn more about getting Fast, sustained relief from HAE attacks with BERINERT
How quickly does BERINERT start to work?
BERINERT provides fast onset of relief from HAE attacks in as little as:
  • 15 minutes for laryngeal attacks. The time to complete resolution of symptoms was 8.4 hours.
  • 48 minutes for abdominal and facial attacks. The time to complete resolution of symptoms was under 5 hours.
Explore more about fast relief from HAE attacks with BERINERT
Can I self-administer BERINERT?
BERINERT is an intravenous (IV) injection that, with proper training, you can infuse on your own or with the help of a caregiver at the first sign of an HAE attack. Learning how to self-administer BERINERT can give you or your caregiver the confidence to treat attacks at the first sign.

Learn more about self-administering BERINERT
The safety of BERINERT was proven in both adults and children. The most serious adverse reaction reported in subjects who received BERINERT in clinical studies was an increase in the severity of pain associated with HAE. Dysgeusia, a bad taste in the mouth, was the most common adverse reaction reported in over 4% of subjects and more frequently than in the placebo group.

Learn more about the efficacy and safety of BERINERT
How do I know if BERINERT is right for me?
If you are experiencing acute abdominal, facial, or throat (laryngeal) attacks of hereditary angioedema, you may be ready to explore treatment options or look for an alternative to what you are currently taking. BERINERT is one therapy you may want to consider, but only you and your doctor can decide if BERINERT is right for you.

Explore fast, sustained relief from HAE attacks
What is the BERINERT Connect support program?
BERINERT Connect gathers many resources in one place to provide assistance, information, and support—all with a single phone call. Once your doctor prescribes BERINERT, you’ll have access to help getting started, financial support, connections with others living with HAE, and so much more.

Explore all the services available through BERINERT Connect

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