During an HAE attack, patients treating with on-demand therapy need the right dose at the first sign of an attack. With BERINERT, patients can self-administer an appropriate dose when and where they need to.
BERINERT delivers an individualized amount of C1-INH for every patient.
|Patient weight||Units||Minutes||# of vials|
|20 kg/44 lb||400 IU||2 min||0.8 vial|
|45 kg/99 lb||900 IU||4.5 min||1.8 vial|
|70 kg/154 lb||1400 IU||7 min||2.8 vial|
Quickly calculate the recommended dose for your patient by entering their body weight.
Enter body weight
BERINERT dose and infusion time
View step-by-step instructions on how to self-administer BERINERT by intravenous infusion.
Download and keep the Self-administration Guide for when you or your patients need it.
Watch step-by-step instructions on how to self-administer BERINERT by intravenous infusion.
Gather your supplies
Step 1. Inspect both vials
Step 2. Wash your hands and clean surface
Hint: Use your Self-Administration Mat, which is designed to help you organize your supplies.
Step 3. Open the Mix2Vial® transfer set
Step 4. Sanitize the water vial and connect
Hint: The blue end locks onto the water vial (easy to remember: “blue” for water).
Step 5. Remove the Mix2Vial® cup
Step 6. Connect the water vial and Berinert vial
Step 7. Dissolve Berinert powder
Step 8. Open the Mix2Vial® transfer set
Step 9. Inspect the solution and draw it into a syringe
Repeat if necessary
Read before infusing
Please note that there are limited data on the use of this medicinal product in home or by self-administration. Your prescribing physician may decide that Berinert can be self-administered by a patient at home or by another nonhealthcare professional, such as a family member. Before Berinert can be safely and effectively administered at home, the person charged with infusing must have the necessary skills. Please do not try to self-administer unless you have received specific training and approval from your prescribing physician.
If you will be infusing at home, please follow the instructions for properly storing Berinert. You can find them in the package insert (prescribing information). Your prescribing physician will let you know when and in what dose to infuse Berinert. Depending on your dose, you might have to infuse several vials.
Seek immediate emergency medical treatment if you cannot enter a vein or if your attack has progressed to a point where you are unable to successfully reconstitute or administer Berinert. Contact your physician or seek emergency care if the medicine does not work or if you experience adverse reactions.
After self-administering for laryngeal attacks of HAE, seek immediate medical treatment. Inform your physician if you administer for abdominal attack of HAE, particularly if the medication does not appear to be effective, as other causes might need to be ruled out.
Gather your supplies
Inspect vials and sanitize
Hint: Use your Self-Administration Mat, which is designed to help organize your supplies.
Prepare the syringe for self-administration
Step 1. Prime (fill) the infusion set
Step 2. Prepare the infusion site
Step 3. Insert needle
Step 4. Check needle for proper placement
Step 5. Start infusion
Step 6. Remove the needle
Step 7. Cover the infusion site and clean up
Step 8. Record your infusion details